Structural Cell Biology: Centriole Architecture and Assembly
The lab focuses on deciphering the structural mechanisms governing centriole assembly. To this end, we are combining the use of cell biology methods, in vitro reconstitution assays, cryo-microscopy / cryo-tomography and super-resolution microscopy to gain decisive insights into these mechanisms.
Structure of the centriolar core region . Left: Paramecium. Right: Chlamydomonas - See Le Guennec et al. Science Advances. 2020.